Optimizing the diagnosis of leukemia through deep learning: assessment of economic efficiency and management potential
Abstract and keywords
Abstract:
The research is devoted to the development and comprehensive evaluation of a deep learning algorithm for automating a key stage in the diagnosis of acute lymphoblastic leukemia (ALL) — morphological analysis of blood cells. The aim of the work is to bridge the gap between the technical validation of AI and the assessment of its economic and managerial potential. Based on a representative clinical dataset (15,135 images), the EfficientNetB3 model achieved 97.5% accuracy, 96.2% sensitivity, and 97.8% specificity (AUC-ROC = 0.987). The key result is a quantitative assessment of the operational effect: economic and temporal simulation has shown that using the algorithm as a pre-selection system can reduce the time of routine screening by a specialist by 70-85%. This frees up the most valuable resource — the expert's time — to solve complex problems. It is concluded that the implementation of such solutions leads to three main results: improving the operational efficiency of the laboratory, standardizing the quality of diagnostics, and transforming the specialist's work towards higher added value. Thus, the work demonstrates that AI technologies are not just a tool for improving accuracy, but a strategic investment in creating a more sustainable and cost-effective healthcare system.

Keywords:
acute lymphoblastic leukemia, artificial intelligence, deep learning, diagnostics, healthcare economics, operational efficiency.
Text
Text (PDF): Read Download
References

1. Balasamy, K. Medical Image Analysis Through Deep Learning Techniques: A Comprehensive Survey / K. Balasamy, V. Seethalakshmi, S. Suganyadevi // Wireless Personal Communications. – 2024. – Vol. 137, No. 3. – P. 1685-1714. – DOIhttps://doi.org/10.1007/s11277-024-11428-1. – EDN NTWQIE.

2. CerConvNet: Cervical Cancer Cells Prediction Using Convolutional Neural Networks / P. M, S. Patil, M. M V [et al.] // Informatica (Ljubljana). – 2024. – Vol. 48, No. 3. – DOIhttps://doi.org/10.31449/inf.v48i3.5905. – EDN AGZDTD.

3. Gupta A., Gupta R. ALL Challenge Dataset Of ISBI 2019 [Electronic resource] : [dataset] / A. Gupta, R. Gupta. — The Cancer Imaging Archive, 2019. - Access mode: https://doi.org/10.7937/tcia.2019.dc64i46r (accessed: 12/20/2025).

4. Simulation of computer image recognition technology based on image feature extraction / W. Ying, L. Zhang, Sh. Luo [et al.] // Soft Computing - A Fusion of Foundations, Methodologies and Applications. – 2023. – Vol. 27, No. 14. – P. 10167-10176. – DOIhttps://doi.org/10.1007/s00500-023-08246-1 . – EDN LIKRVQ.

5. Tens of images can suffice to train neural networks for malignant leukocyte detection / J. P. E. Schouten, Ch. Matek, L. F. P. Jacobs [et al.] // Scientific Reports. – 2021. – Vol. 11, No. 1. – P. 7995. – DOIhttps://doi.org/10.1038/s41598-021-86995-5. – EDN BVYBMQ.

6. Topol, E. J. High-performance medicine: the convergence of human and artificial intelligence / E. J. Topol // Nature Medicine. – 2019. – Vol. 25, No. 1. – P. 44-56. – DOIhttps://doi.org/10.1038/s41591-018-0300-7. – EDN OQSRZW.

7. Alimbayev, A. N. A. N. Methodology for assessing the social and economic effectiveness of digitalization of healthcare systems / A. N. A. N. Alimbayev, B. N. S. N. Bitenova, T. N. Prize winner. Yesenbekova / / Economics: strategy and practice. – 2020. – Vol. 2. 15, No. 3. - S. 13. 25-37. – EDN DRBYWS.

8. Gorodnova, N. V. N. Improving the quality of life of Russian citizens in the process of implementing innovative projects / N. V. N. Gorodnova, N. A. N. Samarskaya / / Issues of innovative economics. – 2019. – Vol. 2. 9, No. 3. - S. 13. 721-734. – DOIhttps://doi.org/10.18334/vinec.9.3.40917. – EDN IACEXD.

9. Application of machine learning algorithms to develop a model for predicting the survival rate of lung cancer patients in the Republic of Kazakhstan / V. A. N. Makarov, D. N. R. Kaidarova, S. N. E. N. Esentayeva [et al.] / / Oncology and radiology of Kazakhstan. – 2022. – № 3(65). - C. 13. 4-11. – DOIhttps://doi.org/10.52532/2521-6414-2022-3-65-4-11. – EDN VSAJZG.

10. Ryabova, T. N. F. N. The quality of life of the Russian population: state, problems, prospects / T. N. F. N. Ryabova, N. M. N. Surai / / Economy. Profession. Business. – 2022. – No. 2. - S. 13. 98-106. – DOIhttps://doi.org/10.14258/epb202227. – EDN JRMJIK.

Login or Create
* Forgot password?